By Dr. Mercola
Surprisingly, despite the dramatically increased risk of cancer
and related adverse health effects associated with smoking
cigarettes, smoking has actually been found to be associated
with a reduced risk of Parkinson’s disease, a
neurodegenerative disorder of the central nervous system.
The most obvious symptoms of Parkinson’s are
movement-related, e.g. shaking and rigidity. This apparently
beneficial link with smoking is often attributed to the nicotine
in cigarettes, which is thought to have a potentially
neuroprotective effect.
Certain foods contain natural amounts of nicotine, including
peppers, which researchers recently found may also reduce the
risk of Parkinson’s.
Eating Peppers May Reduce Parkinson’s Risk by 19 Percent
Peppers are a member of the Solanaceae family of vegetables,
informally known as nightshades, which also includes tobacco,
tomatoes and potatoes.
Upon analyzing the vegetable consumption, tobacco and
caffeine use of nearly 500 newly diagnosed Parkinson’s patients
as well as a group of healthy controls, researchers found that
eating peppers – but not other vegetables in the Solanaceae
family -- was associated with a 19 percent lower risk of
Parkinson’s.1
The association was strongest among those who had never
smoked. Researchers said in a statement:2
“Similar to the many studies that indicate tobacco
use might reduce risk of Parkinson's, our findings also
suggest a protective effect from nicotine, or perhaps a
similar but less toxic chemical, in peppers and tobacco."
Parkinson's disease is a neurological disorder in which
neurons in a region of dopamine-producing cells within your
brain known as the substantia nigra, required for normal
movement, begin to die.
As a disease that currently cannot be cured, prevention
of Parkinson’s disease is crucial. Eating a varied whole-foods
diet that includes healthful veggies like peppers appears to be
one simple way to lower your risk, especially since a lack of
folate is also linked to Parkinson’s (and veggies are the only
source of this important vitamin; most vitamins contain the
semi-synthetic analog known as folic acid).
Caffeine, Omega-3 Fats and Other Dietary Strategies to Help
Prevent Parkinson’s
In addition to dietary nicotine, dietary caffeine, such as
that from coffee, has also been linked to a lower risk of
Parkinson’s. One study even found that the daily caffeine
equivalent in two to four cups of coffee may modestly improve
Parkinson’s movement symptoms.3
Caffeine, which is doparminergic (stimulates dopamine
release), may be one reason why green tea has also been linked
to a lower Parkinson’s risk, although one study suggested that
it’s green tea’s polyphenols that offer neuroprotection that
might benefit Parkinson’s patients.4
Another important consideration are animal-based omega-3
fats, which may protect against Parkinson’s by preventing the
misfolding of a protein resulting from a gene mutation in
neurodegenerative diseases like Parkinson's and Huntington's.5
Animal-based omega-3 fats contain two fatty acids crucial to
human health, DHA and EPA. Most of the neurological benefits of
omega-3 oils are derived from the DHA, which is one of the major
building blocks of your brain.
About half of your brain and eyes are made up of fat, much of
which is DHA -- making it an essential nutrient for optimal
brain function. Your brain activity actually depends greatly
upon the functions provided by its outer, fatty waxy membrane to
act as an electrical nerve-conduction cable, so adding omega-3
fats to your diet, via wild-caught fish or a supplement like
krill oil, is important.
Vitamin D and CoQ10: Two Nutrients for Parkinson’s Protection
There is a correlation between insufficient levels of vitamin
D and the development of early Parkinson's disease. It used to
be thought that vitamin D deficiency is a symptom of
Parkinson's, but recent research squarely implicated vitamin D
deficiency as one of the causes of Parkinson's.6
The best way to optimize your vitamin D level is through
midday sun exposure or a safe tanning bed as that virtually
eliminates any risk of overdose. As a very general guide, you
need to expose about 40 percent of your entire body to the sun
for approximately 20 minutes between the hours of 10 am and 2
pm, or until your skin turns the lightest shade of pink.
If you’re using an oral supplement, recent studies suggest
adults typically need about 8,000 IU’s of oral vitamin D3 per
day in order to get serum levels above 40 ng/ml. However,
remember that if you take oral vitamin D, you also need to boost
your vitamin K2, either through your food choices or a
supplement, as this will prevent soft tissue calcification. You
can find more details on
optimizing your vitamin D levels here.
Another often-overlooked nutritional consideration for
Parkinson’s is the antioxidant compound coenzyme Q10 (CoQ10),
levels of which are often low in people with the disease. One
study found that the progression of Parkinson's disease was
significantly slower in people taking the highest dose of CoQ10.7
If you’re taking statin cholesterol-lowering drugs, this issue
is particularly important as these medications deplete your body
of CoQ10, among over 300 other
statin linked adverse health effects, making supplementation
with CoQ10 (or ideally, the reduced form, called ubiquinol)
important.
Environmental Toxins Likely Play a Role in Parkinson’s
Development
The risk of Parkinson’s disease clearly increases with
exposure to certain environmental toxins. For instance,
neurotoxins like pesticides, herbicides and fungicides are
substances that have been shown to cause disruptions and/or
damage to the neurological system, including your brain.
Rotenone and paraquat are two specific pesticides linked to an
increased risk of Parkinson's disease, and both are lipophilic,
meaning they resist breaking down in water and accumulate in
your fat. Both are also known to cross your blood-brain barrier.
Even ambient exposure to pesticides has been found to
increase the risk of Parkinson’s disease “considerably.”8
Exposure to industrial solvents, including TCE, a common
degreasing agent and dry-cleaning chemical, is also linked to
Parkinson’s disease,9
further strengthening the link between this disease and
environmental toxins. Along with avoiding the use of solvents
and pesticides in your home and garden, eating organic foods as
much as possible will help you avoid unnecessary exposure to
chemicals like pesticides.
This is all the more important today considering that
glyphosate-based herbicides such as Roundup have also been
linked to Parkinson’s-related disorders, and these chemical
residues can be found in virtually all food containing GMOs.10
Another important and often-overlooked risk factor is “silver”
amalgam dental fillings, which contain mercury. Mercury becomes
a biochemical train wreck in your body, causing your cell
membranes to leak, and inhibits key enzymes your body needs for
energy production and removal of toxins.
Mercury toxicity can lead to major inflammation and chronic
illnesses such as Parkinson’s disease.
Lifestyle Changes are Important in Preventing Parkinson’s
Disease
Parkinson's disease is still classified as idiopathic,
meaning it has no identifiable cause. However, just as
researchers identified that eating peppers may be able to lower
your risk, and pesticides and other environmental toxins have
been shown to increase your risk, there are steps you
can take to modify your risk of this disease. To recap some of
the most important, as well as add a few additional
recommendations:
- Avoid pesticide and insecticide exposure (as well as
exposure to other environmental toxins like solvents)
- Exercise regularly. It's one of the best ways to protect
against the onset of symptoms of Parkinson's disease
- Get plenty of sunshine to optimize your vitamin D levels
- Eat more vegetables, which are high in folic acid
- Make sure your body has healthy levels of iron and
manganese (neither too much nor too little of either)
- Consider supplementing coenzyme Q10 or its reduced form
Ubiquinol, which may help to fight the disease
© Copyright 1997-2013 Dr. Joseph Mercola. All Rights Reserved.