Experimental results are sometimes so paradoxical and downright weird that they open up never-imagined possibilities�and force researchers to rethink previous notions. Just such a finding surfaced in a study that gave mice a drug used to suppress the immune system and found that it bolstered the powers of an influenza vaccine. The drug's surprising impact on the immune system may offer a way to elicit more effective antibody responses from vaccines against myriad other diseases.