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Genetic Engineering page
Thirteen years after Golden Rice was
featured on the cover of
Time magazine under the headline "This Rice Could Save a
Million Kids a Year," biotech's golden child is back in the
headlines. Just when public opposition to genetically modified
organisms (GMOs) is at an all-time high, and the biotech and
junk food industries are once again pouring millions of dollars
into a
campaign to defeat laws that would require labels on foods
containing GMO ingredients.
Coincidence? Industry spokespeople say the suspiciously timed
resurrection of Golden Rice in the news is not a public
relations stunt aimed at converting GMO skeptics. But absent any
new news on a crop that hasn't gained traction in more than a
decade, the move looks more like an act of desperation than a
legitimate defense of biotechnology.
After all, in the real world, the genetic engineering that has
taken over vast tracts of cropland, the kind that has led to
the proliferation of crops that require drenching our soil and
polluting our waterways with obscene amounts of toxic herbicides
and pesticides, has little in common with the DNA tinkering that
produced Golden Rice.
But the real issue is this. Golden Rice is no closer to saving
the world's kids than it was 13 years ago. Because then, as now,
there is still no proof that it can. And better alternatives
exist.
In case you missed the fuss, in a nutshell, Golden Rice is
engineered to contain high amounts of Vitamin A. Its target
market includes children in impoverished regions of the world
who are susceptible to blindness resulting from diets deficient
in Vitamin A. The grain's first iteration, GR1, was discovered
to contain Vitamin A in quantities too low to make a difference.
GR1 was followed by GR2, engineered to contain Vitamin A in much
higher quantities.
More Vitamin A in a bowl of rice, better nutrition, healthier
kids. It sounds good on the surface, but as scientists point
out, it's not that simple. Here are just a few of the reasons
scientists say Golden Rice is not a silver bullet.
The wrong food for the wrong
regions.
According to Dr. Michael Hansen of the Union of Concerned
Scientists, both GR 1 and GR 2 (released in 2005) are Japonica
rices - the sticky, short-grained variety that grows only in
drylands. But in the areas where people are starving and/or
Vitamin A-deficient, the vast majority of the population eat
Indica rice, a long-grained variety that grows in submerged rice
paddies.
And, as food writer Beth Hoffman
wrote recently in Forbes
magazine, Africans, who make up 25-35 percent of the world's
Vitamin A-deficient population, don't eat rice:
Therefore, even more than
convincing people to switch from white sweet potatoes to orange,
for example, or from yellow corn to that with a more orange hue,
the challenge of getting large numbers of Africans to eat Golden
Rice will be enormous.
Not proven safe.
What little safety testing that has been done on Golden Rice has
been inadequate and controversial. In February 2009, a group of
22 international scientists and experts
complained that clinical trials of Golden Rice had been
conducted on adults and children, in breach of the Nuremberg
Code, and that the trials had been "inadequately described in
terms of biological and biochemical makeup."
In an open letter to Prof. Robert Russell at Tufts University
School of Medicine, who was in charge of the clinical trials,
the scientists backed up their concerns with a large body of
evidence showing that genetically engineered crops produce
unintended effects, which can result in damage to health. "There
is no evidence to suggest that Golden Rice is any safer than
these GM foods," the scientists concluded.
Other scientists, including Hansen, question Golden Rice's
safety on the basis of its containing retinoic acid (RA). RA is
a potent teratogen, which is a substance linked to birth
defects. Hansen points out that RA is the active ingredient in
an acne medication that will not be prescribed to women of
childbearing age.
When I pointed out at the
Philippine House of Representatives that GR experiment led to an
unexpected increase in β-carotene, and that they should look at
RA levels, since there are only two steps in a metabolic pathway
between β-carotene and RA, and since trying to engineer
biosynthetic pathways can cause all sorts of unintended effects,
the IRRI scientist could produce no data on RA levels, much less
the levels of other retinoids. He argued that people have been
eating foods such as carrots, that are high in β-carotene levels
(higher than the levels of GR), for hundreds of years, yet
there's no evidence of a big problem with birth defects. I had
to point out that people and the food they eat have long
co-evolutionary history. If there had been varieties of carrots
that did have high RA levels that lead to birth defects, those
carrot varieties would tend not to be used over time.
No proof of beta carotene
stability over time.
Beta carotene, the primary source of Vitamin A in Golden Rice,
breaks down when exposed to oxygen and light. That leads experts
to wonder if genetically engineered Golden Rice that has been
stored for several months still provides higher levels of
Vitamin A. We don't know, because we have no studies on the
longer-term stability of beta carotene in Golden Rice. Says
Hansen:
So, the real question is what are the β-carotene levels in rice
that has sat in storage at room temperature for month or two,
similar to the local storage conditions for those who might grow
this rice. Again, no studies have been done.
Better Vitamin A alternatives
exist.
As World Health Organization (WHO) nutrition expert Francesco
Branca and more recently, Michael
Pollan and others point out, there are better ways to
provide Vitamin A-rich diets than relying on an unproven
genetically modified "techo solution." That was also the
conclusion drawn back in 2009, by Dr. Mae-Wan Ho and Prof. Joe
Cummins of Institute of Science in Society, who advocated a
combination of food fortification, food supplements and general
improvements in diets as a way to improve both Vitamin A
consumption and absorption. They cited a United Nations Food and
Agricultural Organization (FAO) study that revealed that the
absorption of pro-vitamin A depends on a person's overall
nutritional status, which in turn depends on the diversity of
the food consumed. Ho and Cummins wrote:
The main cause of hunger and
malnutrition in the Third World is the industrial monocultures
of the Green Revolution, which obliterated agricultural
biodiversity and soil fertility, resulting in ever-worsening
mineral and micronutrient deficiencies in our food. Golden Rice,
like other GM crops, is industrial monoculture only worse, and
will exacerbate this trend, as well as the destruction of
agricultural land, and the impoverishment of family farmers that
also accompanied the Green Revolution.
Golden Rice is a long way from
reality.
As food writer Beth Hoffman put it in her
recent post in Forbes
magazine:
Golden Rice remains a
theoretical product with many, many questions and logistics to
still be figured out, aimed at serving a hypothetical population
who might actually benefit from its invention, if and when it
becomes both viable and legally available.
In the meantime, the Golden Rice story remains little
more than a thinly disguised, if
well-funded, public relations ploy intended to distract
consumers from the very real threat GMOs pose to our health,
safety and our increasingly depleted and polluted soil and
water.
Katherine Paul is director of
communications for the
Organic
Consumers Association.
Ronnie Cummins is national director of the
Organic
Consumers Association.
http://www.organicconsumers.org/articles/article_28251.cfm