Can Aspirin Help Prevent Alzheimer's?
Tuesday, 01 Dec 2015 11:00 AM
A key component of aspirin has been found to block a process in the development of Alzheimer’s disease, as well as Parkinson’s, Huntington’s and other neurodegenerative disorders.
Researchers at the Boyce Thompson Institute and John Hopkins University discovered that salicylic acid, the primary byproduct of aspirin, binds to a cellular enzyme called GAPDH. That stops it from causing cell death – a key mechanism in the development of Alzheimer’s and other brain disorders.
The study, which appears in the Public Library of Science journal PLOS ONE, suggests that derivatives of salicylic acid may hold promise for treating multiple neurodegenerative diseases.