Millions of Genetically Modified
Mosquitoes Could Be Released in Florida
March 03, 2015
Story at-a-glance
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Biotech company Oxitec and the Florida Keys Mosquito Control
District (FKMCD) are moving forward to introduce genetically
modified (GM) mosquitoes to the area in an attempt to stop
the spread of two tropical diseases
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FKMCD states that “Dengue fever and chikungunya are
currently not an active health threat in the Florida Keys”
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The GM mosquitoes contain protein fragments from the herpes
virus, E. coli bacteria, coral, and cabbage
By Dr. Mercola
Chikungunya and dengue are tropical diseases spread by Aedes
mosquitoes. Infection with the chikungunya virus leads to fever and
joint pain that can be severe, although it rarely causes death.
Chikungunya occurs regularly in Africa, Asia, and India, and in
2013 it was first detected in the Caribbean. In 2014, there were
just over 2,300 cases of chikungunya reported in the US.
However, only 11 individuals actually contracted the disease in
the US (in Florida). All the others were cases that occurred in
travelers returning from other affected areas in the Caribbean or
Pacific Islands.1
Symptoms of infection with dengue virus are slightly different –
high fever, severe headache, and pain in the eyes, joints, muscles,
and bones are common. In severe cases, dengue may progress into
dengue hemorrhagic fever, which causes vomiting abdominal pain,
bleeding, and trouble breathing, and may be deadly.
It’s estimated that more than 100 million cases of dengue occur
worldwide each year,2
including in Puerto Rico, Latin America, Southeast Asia, and the
Pacific Islands. However, according to the US Centers for Disease
Control and Prevention (CDC), “dengue rarely occurs in the
continental United States.”3
While, theoretically, both chikungunya and dengue could spread
throughout the US, particularly in tropical and Southern states,
this hasn’t happened yet. We’ve seen only a handful of locally
transmitted cases…
GM Mosquitoes May Be Released in the Florida Keys in 2015
Unfortunately, biotech company Oxitec and the Florida Keys
Mosquito Control District (FKMCD) are moving forward on their plan
to introduce
genetically modified (GM) mosquitoes to the area in an attempt
to stop the spread of these tropical diseases.
Ironically, FKMCD states flat out: “Dengue fever and chikungunya
are currently not an active health threat in the Florida Keys.”4
Yet, they’re apparently willing to risk the unknown consequences of
releasing a GM species into the wild anyway.
The plan is currently being reviewed by the US Food and Drug
Administration (FDA). If it is approved, GM male mosquitoes would be
released into the Florida Keys up to three times a week, starting
sometime in 2015.
The Oxitec mosquitoes are unlike any that exist in nature.
They’ve been genetically altered to carry a “genetic kill switch,”
such that when they mate with wild female mosquitoes, their
offspring inherits the lethal gene and cannot survive.5
To achieve this feat, Oxitec has inserted protein fragments from
the herpes virus, E. coli bacteria, coral, and cabbage into the
insects, dubbed as OX513A. The GM mosquitoes have proven lethal to
native mosquito populations.
In the Cayman Islands, for instance, 96 percent of native
mosquitoes were suppressed after more than 3 million GM mosquitoes
were released in the area, with similar results reported in Brazil.6
But as we’ve seen in the past with genetically modified organisms
(GMOs), when you tinker with nature, it often comes back to bite
you.
Problems with GM Mosquitoes
One of the first questions that comes to mind is, what happens if
one of the GM mosquitoes bites you? Will their GM DNA be injected
into your arm or leg? Oxitec has counteracted this objection by
stating they only plan to release male mosquitoes, which
don’t bite.
This again sounds good in theory… but in reality,
sorting millions of insects according to sex is no small feat. And
even FKMCD notes that although “every effort is made to release only
males,” Oxitec trials show that .03 percent of the mosquitoes
released are female.7
So it’s not only males being released. If 3 million
mosquitoes are released, as they were in the Caymans, data from
Oxitec trials suggest about 900 of them will be female –
and capable of biting. Even so, FKMCD states “there’s no difference
between the bite of an Oxitec female and a wild one.”
It’s unclear on what research they are basing this assumption.
The AP reported that Oxitec has released 70 million GM
mosquitoes thus far, with no reports of “human impacts caused by
bites or from the synthetic DNA.”8
What the heck does that mean? Who would even know to report or
where?
Also, the mosquitoes haven’t been around long enough to assume
there will be no impacts. There are several glaring problems with
assuming these GM bugs are safe for the human population.
For starters:
- The potential exists for these genes, which hop from one
place to another, to infect human blood by finding entry through
skin lesions or inhaled dust. Such transmission could
potentially wreak havoc with the human genome by creating
"insertion mutations" and other unpredictable types of DNA
damage.10
- According to Alfred Handler, a geneticist at the Agriculture
Department in Hawaii, mosquitoes can develop resistance to the
lethal gene and might then be released inadvertently.
Todd Shelly, an entomologist for the Agriculture Department
in Hawaii, said 3.5 percent of the insects in a laboratory test
survived to adulthood, despite presumably carrying the lethal
gene.11
- Tetracycline and other antibiotics are now showing up in the
environment, in soil and surface water samples. These GM
mosquitoes were designed to die in the absence of tetracycline
(which is introduced in the lab in order to keep them alive long
enough to breed).
They were designed this way assuming they would NOT have access
to that drug in the wild. With tetracycline exposure (for example,
in a lake) these mutant insects could actually thrive in
the wild, potentially creating a nightmarish scenario.
Florida Keys Residents Slated to Become the Next Guinea Pigs
Many residents of the Florida Keys are understandably upset.
They’re slated to become the next guinea pigs in this human
experiment. Residents and tourists in the Cayman Islands know that
feeling all too well.
In 2009, Oxitec released their GM bugs onto Grand Cayman Island
in the Caribbean. The experiment will go down in scientific
history as the first release of GM insects that could bite humans.
Not surprisingly, it was conducted in secret.
Once the locals got wind of this, they responded with a fair
amount of public outrage—and rightly so! But it didn't stop there.
Oxitec subsequently released their frankenskeeters in Malaysia,
Brazil, Panama, India, Singapore, Thailand, and Vietnam. The
Institute for Science in Society (ISIS) wrote at the time of the
Cayman Island release:12
“ …the current release of terminator male mosquitoes on
Cayman Island is a risky strategy. To add insult on injury,
there has been no warnings issued to tourists, and most
residents on the Island do not appear to have given informed
consent to be exposed to the GM male mosquitoes, in blatant
violation of human rights with regard to human experimentation.
If the strategy has succeeded, as claimed, the islanders
may have been granted temporary respite from the insect vector
for Dengue; though replacement mosquito vectors are likely to be
blown in from neighboring islands almost immediately while GM
mosquitoes are spreading to them from Cayman Island.
The UK government appears not to have exercised appropriate
jurisdiction over the human experimentation in its territory;
while the scientific community should condemn the use of data to
justify the experiment from studies that had not passed peer
review.”
Too Late: GM Insects Released Before Their Full Consequences Are
Understood
If you’re surprised to learn that GM mosquitoes have already been
released into the wild, you might be shocked to know that Oxitec is
also the creator of genetically modified pink bollworm moths, and
swarms of this creature have already been unleashed over the fields
of Arizona in an effort to overtake natural bollworm populations,
which are a pest.
In addition, Oxitec has created a genetically engineered
diamond-back or cabbage moth, while other groups are also developing
GM insects. One group has created Anopheles mosquitoes that
are immune to the malaria parasite they normally carry, and also
manufacturing male Anopheles that lack sperm.
It may sound exciting – a way to control pests without pesticides
and stop the spread of deadly diseases! – but this is uncharted
territory. At present, the use of GM insects is in its infancy. Not
only are there no precedents from which to draw potential ecological
consequences, but proper risk assessments have not been done – and
quite possibly might be impossible to conduct, considering the many
unknown aspects of tinkering with DNA and allowing it to
mingle with other species. In a study published in Ecology and
Evolution, researchers attempted to identify potential
ecological effects of GM insects, and revealed many along with
important knowledge gaps.
They wrote:13
“The effects may occur in two phases: a transitory phase
when the focal population changes in density, and a steady state
phase when it reaches a new, constant density… Our methodology
reveals many potential effects in each phase, perhaps most
notably those dealing with immunity in the transitory phase, and
with pathogen and vector evolution in the steady state phase.
Importantly, this framework identifies knowledge gaps in
mosquito ecology.
…For instance, in evaluating GE mosquitoes, the knowledge
gaps in mosquito ecology are striking… particularly with respect
to mosquito effects on consumer and resource species. Data and
theory on ecological hysteresis in insect communities are also
lacking, which makes it difficult to assess whether any changes
are irreversible.”
Sign the Petition to Keep GM Mosquitoes Out of the Florida Keys
There are far more questions than answers surrounding GM insects
at this time, and the FDA should not allow this type of reckless
experimentation to take place. As a Change.org petition explains:14
“Nearly all experiments with genetically-modified crops
have eventually resulted in unintended consequences: superweeds
more resistant to herbicides, mutated and resistant insects also
collateral damage to ecosystems. A recent news story reported
that the monarch butterfly population is down by half in areas
where Roundup Ready GM crops are doused with ultra-high levels
of herbicides that wipe out the monarch's favorite milkweed
plant.
What about our native species of Florida Keys Bats. Are
there any studies being conducted to see if these mosquitoes
will harm the native bat population? Why would we not expect GM
(genetically modified) insects, especially those that bite
humans, to have similar unintended negative consequences? Will
the more virulent Asian tiger mosquito that also carries dengue
fill the void left by reductions in A. aegypti? Will the dengue
virus mutate (think antibiotic resistant MRSA) and become even
more dangerous?”
We’re already seeing the unintended consequences of GM crops
popping up… “super weeds” and increasingly resistant pests are
rapidly spreading and wreaking havoc across American farmland, while
the
human health concerns keep mounting. When scientists take
genetic modification even further, tinkering with genes in insects
and animals, the consequences may be even steeper.
When a Purdue University computer model tracked the effects of
releasing just 60 “Frankenfish” (genetically modified salmon) into a
population of 60,000, there was a
complete extinction of the normal fish in just 40 fish
generations… The Change.org petition is calling for the FDA to
reject the release of GM mosquitoes in the Florida Keys. You can
sign the petition now to voice your support.
Copyright 1997- 2015 Dr. Joseph Mercola. All Rights Reserved.
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