Marijuana may hold the key to a new treatment for Alzheimer's
disease, a new study suggests.
The research, published in the journal Aging and Mechanisms of
Disease, identified a compound present in marijuana that triggered
the removal of beta-amyloid protein from nerve cells in the brain,
Huffington Post
reports. Beta-amyloid is a hallmark of Alzheimer’s disease, forming
clumps in the brain that disrupt communication between neurons.
For the new study, David Schubert, of the Salk Institute for
Biological Studies , and colleagues modified nerve cells to produce
high levels of the protein in the lab. They then applied a chemical
in marijuana, called tetrahydrocannabinol (THC), to nerve cells with
high beta-amyloid production.
They found that the THC reduced beta-amyloid levels and
eradicated the cells' inflammatory response to the protein,
which prevented nerve cell death.
The researchers believe their findings shed more light on the
role beta-amyloid plays in Alzheimer’s disease, which could pave
the way for new treatments.
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